Sakamoto KM and D Frank. CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy. Clinical Cancer Research, in press. Sandoval S, Pigazzi M, and KM Sakamoto. CREB: A Key Regulator of Normal and Neoplastic Hematopoiesis. Adv Hematol, in press.
Cheng JC, Kinjo K, Wu WS, Schmid I, Shankar DB, Stripecke R, Kasahara N, Bhatia R, Landaw EM, and KM Sakamoto. CREB is a critical regulator of normal hematopoiesis and leukemogenesis, Blood, 111: 1182-1192, 2008.
Danilova N, Sakamoto KM, and S Lin. Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood, Epub May 30, 112(13):5228-37, 2008.
Rodriguez-Gonzalez A, Cyrus K, Salcius M, Kim KB, Crews CM, Deshaies RJ, and KM Sakamoto. Targeting Steroid Hormone Receptors for Ubiquitination and Degradation in Breast and Prostate Cancer, Oncogene, 27:7201-11, 2008.
Shankar DB, Li J, Tapang P, McCall JO, Pease LJ, Dai Y, Wei RQ, Albert DH, Hartandi K, Michaelides M, Davidsen SK, Priceman S, Chang J, Shah N, Moore TB, Sakamoto KM*, and KB Glaser. ABT-869 a Multi-Targeted Receptor Tyrosine Kinase Inhibitor: Inhibition of FLT3 Phosphorylation and Signaling in AML, Blood, 109(8):3400-8, 2007. (*co-senior author)
Shankar D, Cheng JC, Kinjo K, Wang J, Federman N, Moore TB, Gill A, Rao N, Landaw EM, and KM Sakamoto. The role of CREB as a proto-oncogene in Hematopoiesis and in Acute Myeloid Leukemia. Cancer Cell, 7:351-362, 2005.
Verma R, Peters NR, D’Onofrio, Tochtrop G, Sakamoto KM, Varada R, Fushman D, Deshaies RJ, and RW King. Ubistatins Inhibit Proteasome-Dependent Degradation by Binding the Ubiquitin Chain. Science, 306:117-120, 2004.
Shou W, Sakamoto KM, Keener J, Morimoto KW, Hoppe GJ, Azzam R, Traverso EE, Feldman RFR, DeModena J, Charbonneau H, Moazed D, Nomura M and RJ Deshaies. RENT complex stimulates RNA Pol I transcription and regulates nucleolar structure independently of controlling mitotic exit. Mol Cell, 8: 45-55, 2001.
Sakamoto KM, Crews CC, Kim KB, Kumagai A, Mercurio F, and RJ Deshaies. Protac: A Chimeric Molecule that targets Proteins to the SCF for Ubiquitination and Degradation. Proc Natl Acad Sci USA, 98: 8554-8559, 2001.
Lee H-J J, Mignacca RM, and KM Sakamoto. Transcriptional activation of egr-1 by Granulocyte-Macrophage Colony-Stimulating Factor but not Interleukin-3 requires phosphorylation of CREB on Serine 133. J. Biol. Chem., 270: 15979-15983, 1995.